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Cell aggregate models or spheroid models consist of endothelial cells, astrocytes, and pericytes, which are able to self-organize into spherical structures with astrocyte core, surrounded by pericytes and covered with endothelial cells (Urich et al., 2013)

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Care for chronic conditions such as obesity relies on the medical home: a concept of comprehensive and strategic coordination among multiple providers, such as weight management specialists, behavioral health experts, nutritionists, and primary care, to provide long-term care to patients as they transition from childhood to adolescence and adulthood

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