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Response: We acknowledge that some hospitals may have already invested in compliance and reiterate that we remain committed to the Excessive Radiation eCQM as a patient safety issue for cancer prevention

The study reported that GlyNAC supplementation improved glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, physical function, and multiple hallmarks of aging providing the most comprehensive human clinical evidence to date that glutathione precursor supplementation can reverse measurable age-associated deficits

Standard vitamin C (ascorbic acid) can sometimes be acidic and cause stomach irritation

10.1016/j.redox.2023.103022 84 MeyerB

The structural modifications that extend its half-life also mean it accumulates in the body over time, which is why dose escalation protocols start low and increase gradually

It has been reported that 250 mg of caffeine administered orally can prolong the elimination half-life by approximately 1 h in patients with cirrhosis compared to healthy controls, but the result did not reach statistical significance (Desmond et al., 1980)