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Figure 5 Overall, these results show that a 3-month clinical intervention of L-GSH supplementation in individuals with T2DM resulted in significantly increased levels of IFN-, TNF-, IL-2, and decreased levels of IL-10 when compared to before L-GSH supplementation

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Thus, while acutely administered GLP-1RAs, including liraglutide and semaglutide, do not access most deep brain regions, their actions in and near circumventricular areas are critical for their efficacy as antiobesity medications (83, 84)