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The key components of this mechanism are oxidant stress, with ferrous iron-mediated Fenton reaction and LPO as the terminal events [62]
The most important factor is bioavailability
2020;158:196783e1
Indeed, by combining cellular, proteomic and mitochondrial functional analyses, we obtained complementary lines of evidence that consistently point to mitochondria as a major target of HC activity
Gastrointestinal effects occur in 10-15% of users, with nausea and vomiting being most commontaking doses with food reduces these reactions by up to 40%
Rheumatology (Oxford) 52 (8), 14081417 (2013)
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