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The researchers noted that semaglutide might represent a multiple-domain intervention with a single component, explaining that traditional prevention strategies targeting multiple dementia risk factors have shown only modest and inconsistent results
The drug is being developed by Eli Lilly and Company, the same pharmaceutical manufacturer behind tirzepatide (Mounjaro), which has received MHRA approval in the UK for type 2 diabetes and, more recently, for weight management
Specific antidote treatments may need to be given before the catheter is removed
The AAFP advises that injectable therapy leads to more rapid improvement and should be considered in patients with severe deficiency or severe neurologic symptoms (Langan RC, Goodbred AJ, 2017)
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Its not a starting dose patients must first try the standard dose escalation protocol, which begins at 0.25mg and gradually increases to 2.4mg over several months
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