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The mechanisms are complementary: cerebrolysin provides broad neurotrophic support, Semax upregulates BDNF, and Selank modulates emotional regulation

A precursor for glutamate called alpha-ketoglutarate is created in the mitochondria in the TCA cycle (Krebs cycle, producing ATP energy)

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Ann Rheum Dis 68(2):292293 Fuchs-Telem D, Sarig O, van Steensel MA, Isakov O, Israeli S, Nousbeck J, Richard K, Winnepenninckx V, Vernooij M, Shomron N (2012) Familial pityriasis rubra pilaris is caused by mutations in CARD14

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