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The potential gastrointestinal side effects of these drugs can also further limit food intake, Stanford said, which can "lead patients to avoid certain foods, sometimes worsening nutritional gaps." Therefore, while GLP-1 medication is known for being highly effective, experts warn patients need to ensure they are paying close attention to their dietary needs and wider health while using the drugs

Studies suggest that the VEGF/VEGFR-2 pathway may be particularly relevant, as its activation seems to trigger intracellular signaling cascades that potentially influence endothelial cell migration, proliferation, and survival