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Numerous reports substantiate that CSCs play a crucial role in driving tumor initiation, treatment resistance, recurrence, and metastasis ( Figure 3A )

doi: 10.1128/MICROBIOLSPEC.VMBF-0016-2015 122 Muoz-BonillaA.EcheverriaC.Sonseca.ArrietaM

Ushio-Fukai M, Nakamura Y

These specialized immune cells express GLP-1 receptors and when GLP-1(whether from native production or GLP-1 agonists) activates these IELs via GLP-1R it helps to suppress localized T-cell induced inflammation