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doi: 10.1210/clinem/dgaa839 163 DeswalRNarwalVDangAPundirCS

Bipolar disorder: A landmark RCT (n=75) found that NAC (1,000 mg twice daily for 24 weeks) produced a significant improvement in depression scores (Montgomery-Asberg Depression Rating Scale) in bipolar disorder as an adjunct to usual treatment (Berk et al., Biol Psychiatry, 2008) [74]

*Correspondence: Elias de Frana, [email protected] This article was submitted to Exercise Physiology, a section of the journal Frontiers in Physiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

However, they may not be suitable or necessary for everyone

Giustina, A., Mazziotti, G

This can easily be taken as a supplement