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The copper coordination chemistry of GHK-Cu enables controlled cellular copper delivery while preventing the formation of reactive oxygen species characteristic of free copper toxicity, with the peptide's binding affinity (log K = 16.1) positioning it perfectly within the physiological copper transport hierarchy to facilitate controlled metal transfer to enzymatic targets including lysyl oxidase (essential for collagen cross-linking) and superoxide dismutase (critical for antioxidant defense)

The peptide has shown cytoprotective effects throughout the gastrointestinal tract, musculoskeletal system, nervous system, and cardiovascular system

DHA is key to the proper function of cell membranes

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One is prevention and the other is detoxification