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Susan Lovelle, an expert in lifestyle medicine and holistic health, this trend isnt just about weightIts about the increasing prevalence of related conditions like cardiovascular disease, Type 2 diabetes, and hormonally driven cancers. In her recent presentation for AccessLive, our educational webinar series for physicians, she stresses that these challenges are compounded by lifestyle factors such as chronic stress, poor diet, and insufficient sleep, all of which contribute to systemic inflammation and metabolic imbalances

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Pathways such as the NF-B pathway, the MAPK pathway, and the JAK/STAT pathway have also been recognized by prior studies to play a role in the pathogenesis of BBB integrity disturbance (Kebir et al., 2007)

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