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To this end, SNAP/FLAG-hGLP-1R WT or V229A-expressing adenoviruses were transduced into islets extracted from mice lacking endogenous GLP-1R expression (GLP-1R KO, generated in house )

Sachin, J

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Disruption of calciumphosphate metabolism is another hallmark of CKD, underlying the development of mineral and bone disorders chronic kidney diseasemineral and bone disorder (CKD-MBD), secondary hyperparathyroidism, and vascular calcification

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Currently, cancer treatment faces three main challenges: limitations of traditional drug development models, inherent flaws of single-target drugs, and the complexity of tumor mechanisms