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Analysis of whether thymulin is up-regulating a counterpart anti-inflammatory signaling loop revealed the involvement of an IL-10-sensitive pathway

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Multiple organelles involved in regulating iron metabolism and redox balance, including mitochondria [50-55], endoplasmic reticulum [7, 56, 57], Golgi [58], and lysosomes [59, 60], indicate a complete signaling network to control and perform ferroptosis

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FOXA1 can promote the expression of E-cadherin, while BACH1 inhibits the expression of FOXA1 and genes critical for epithelial cell adhesion, including claudin3 and claudin4, thus promoting the EMT

J Biol Chem 279 : 2897028978