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A study published in The New England Journal of Medicine found that gastrointestinal symptoms were the most common adverse events, but they were typically transient and improved once patients adjusted to the maintenance dose

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Begrndet wird diese Abstufung mit dem hheren Risiko fr Krankheitsprogression und Folgeerkrankungen sowie der mglichen Rolle der Pharmakotherapie als Therapieoption vor einer bariatrisch-chirurgischen Manahme

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For quantitative analysis the proteins were labelled using TMTpro 18-plex isobaric mass tagging reagents (Thermo Fischer Scientific) and analyzed by nanoscale liquid chromatography-tandem mass spectrometry (LC-MS 3 ) according to details described in Supplementary material