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HPLCMS analysis after solubilization with acidified methanol confirmed an almost stoichiometric conversion of 3,4- cis -leucocyanidin ( 6 ) into cyanidin ( 8 ), while the formation of the side products epidihydroquercetin ( 9 ), and quercetin ( 11 ) was reduced (Extended Data Fig
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2004) and disruption of energy metabolism (Chen et al
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