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Mechanically, a distinct group of microRNAs, known as the let-7 family, exhibits the capability to restrict the metabolic rate of glutamine, consequently repressing the activation of B lymphocytes [79]

Adaptive thermogenesis and reduced basal metabolic rate (BMR) during calorie restriction can directly lower body temperature

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Bjelland I, Dahl AA, Haug TT, Neckelmann D