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doi: 10.1093/neuonc/noac138 79 DunnGPBruceATIkedaHOldLJSchreiberRD

The biology is plausible and the animal data is intriguing, but Epithalon currently sits in the category of compelling preclinical evidence awaiting rigorous human validation

Indeed, CAFs establish a metabolic connection with prostate cancer cells, through lactate shuttle and thus contributing to cancer aggressiveness

USA 113 , E1565E1574 (2016)

Testing documentation varies by sellable lot

Materials and Methods Cell Culture HeLa cells were cultured in DMEM +FBS [DMEM without pyruvate and glucose (ThermoFisher, 11966025) supplemented with 25 mM glucose, 10% non-dialyzed FBS (Sigma, F2442) and 1% penicillin/streptomycin] at 37C in 5% CO 2